How does the rotovap evaporator improve the evaporation efficiency of drug raw materials and reduce process energy consumption?

According to the different pressures in the rotovap evaporator, the evaporation technology equipment management can be developed into atmospheric evaporator, pressurized evaporator, and reduced pressure evaporator (rotovap evaporator). According to the different analysis of the use of secondary steam in the enterprise, the evaporation equipment can be mainly divided into single-effect evaporator and multi-effect evaporator, and according to the different types of evaporators, it can be divided into circulating evaporator and single-pass evaporator. Taking the rotovap evaporator as an example, the rotovap evaporator is mainly composed of a main unit, glass parts, a constant temperature lifting bath, etc., and is mainly used for concentration, crystallization, drying, separation and solvent recovery in the pharmaceutical, chemical, and biotherapy industries. Under vacuum, the rotovap evaporator is heated at a constant temperature, and the rotary bottle rotates at a constant speed, so that the material forms a large area of ​​film on the bottle wall, and the solvent in the material is evaporated. The solvent vapor is cooled by the glass condenser and recovered in the collection bottle, which greatly improves the evaporation efficiency.

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Because the water bath temperature of the rotovap evaporator is relatively low, it is particularly suitable for concentration, crystallization, separation and solvent recovery, as well as reflux extraction of biological products that are easily decomposed at high temperatures. "The rotovap evaporator expert said. At present, the rotovap evaporator can be used to concentrate the Chinese medicine extract. By heating the solution to vaporize it, part of the extraction solvent is removed, thereby increasing the solute concentration in the solution. Compared with the general heat transfer process, the rotary evaporation has great advantages. For example, when the boiling point of the solution increases, the vapor pressure of the solution is lower than that of the pure solvent at the same temperature because the solution contains non-volatile solutes. For another example, the energy recovery evaporation process is the solvent vaporization process. Since the latent heat of vaporization of different solvents is large, the energy consumption of the evaporation process is greatly affected. Therefore, energy saving is particularly important in evaporation operations.

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